Most populated ZIP codes in South Carolina
The ZIP codes in South Carolina with the most residents.
| Rank | ZIP code | City | County | Population | Population |
|---|
| 1 | 29072 | Lexington, SC | Lexington County | 69,407 | 69,407 |
| 2 | 29681 | Simpsonville, SC | Greenville County | 68,650 | 68,650 |
| 3 | 29445 | Goose Creek, SC | Berkeley County | 59,227 | 59,227 |
| 4 | 29483 | Summerville, SC | Dorchester County | 59,186 | 59,186 |
| 5 | 29485 | Summerville, SC | Dorchester County | 58,507 | 58,507 |
| 6 | 29730 | Rock Hill, SC | York County | 58,199 | 58,199 |
| 7 | 29732 | Rock Hill, SC | York County | 57,675 | 57,675 |
| 8 | 29579 | Myrtle Beach, SC | Horry County | 56,915 | 56,915 |
| 9 | 29651 | Greer, SC | Greenville County | 56,599 | 56,599 |
| 10 | 29526 | Conway, SC | Horry County | 54,130 | 54,130 |
| 11 | 29486 | Summerville, SC | Berkeley County | 53,975 | 53,975 |
| 12 | 29720 | Lancaster, SC | Lancaster County | 53,584 | 53,584 |
| 13 | 29073 | Lexington, SC | Lexington County | 53,156 | 53,156 |
| 14 | 29223 | Columbia, SC | Richland County | 53,074 | 53,074 |
| 15 | 29464 | Mount Pleasant, SC | Charleston County | 53,045 | 53,045 |
| 16 | 29910 | Bluffton, SC | Beaufort County | 53,019 | 53,019 |
| 17 | 29588 | Myrtle Beach, SC | Horry County | 52,609 | 52,609 |
| 18 | 29229 | Columbia, SC | Richland County | 51,861 | 51,861 |
| 19 | 29501 | Florence, SC | Florence County | 48,673 | 48,673 |
| 20 | 29715 | Fort Mill, SC | York County | 46,865 | 46,865 |
| 21 | 29621 | Anderson, SC | Anderson County | 46,482 | 46,482 |
| 22 | 29607 | Greenville, SC | Greenville County | 46,209 | 46,209 |
| 23 | 29466 | Mount Pleasant, SC | Charleston County | 44,942 | 44,942 |
| 24 | 29687 | Taylors, SC | Greenville County | 44,861 | 44,861 |
| 25 | 29414 | Charleston, SC | Charleston County | 44,727 | 44,727 |
| 26 | 29461 | Moncks Corner, SC | Berkeley County | 43,816 | 43,816 |
| 27 | 29708 | Fort Mill, SC | York County | 43,515 | 43,515 |
| 28 | 29650 | Greer, SC | Greenville County | 42,493 | 42,493 |
| 29 | 29456 | Ladson, SC | Charleston County | 41,214 | 41,214 |
| 30 | 29605 | Greenville, SC | Greenville County | 40,717 | 40,717 |
| 31 | 29803 | Aiken, SC | Aiken County | 40,699 | 40,699 |
| 32 | 29203 | Columbia, SC | Richland County | 40,653 | 40,653 |
| 33 | 29710 | Clover, SC | York County | 40,595 | 40,595 |
| 34 | 29210 | Columbia, SC | Richland County | 39,962 | 39,962 |
| 35 | 29412 | Charleston, SC | Charleston County | 39,256 | 39,256 |
| 36 | 29349 | Inman, SC | Spartanburg County | 39,083 | 39,083 |
| 37 | 29615 | Greenville, SC | Greenville County | 38,811 | 38,811 |
| 38 | 29150 | Sumter, SC | Sumter County | 38,538 | 38,538 |
| 39 | 29063 | Irmo, SC | Richland County | 38,201 | 38,201 |
| 40 | 29209 | Columbia, SC | Richland County | 38,041 | 38,041 |
| 41 | 29707 | Fort Mill, SC | Lancaster County | 37,629 | 37,629 |
| 42 | 29642 | Easley, SC | Anderson County | 36,852 | 36,852 |
| 43 | 29407 | Charleston, SC | Charleston County | 36,706 | 36,706 |
| 44 | 29301 | Spartanburg, SC | Spartanburg County | 36,278 | 36,278 |
| 45 | 29680 | Simpsonville, SC | Greenville County | 35,770 | 35,770 |
| 46 | 29577 | Myrtle Beach, SC | Horry County | 35,446 | 35,446 |
| 47 | 29745 | York, SC | York County | 34,909 | 34,909 |
| 48 | 29576 | Murrells Inlet, SC | Horry County | 34,695 | 34,695 |
| 49 | 29640 | Easley, SC | Pickens County | 33,142 | 33,142 |
| 50 | 29316 | Boiling Springs, SC | Spartanburg County | 33,104 | 33,104 |
Source: American Community Survey 2020–2024 5-year estimates. Only ZIP codes with a delivery area are ranked. Methodology
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