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ZIP code 63341: Defiance, MO

63341 is a ZIP code in Defiance, Missouri, mainly in St. Charles County, part of the St. Louis, MO-IL metro area. About 3,515 people live here.

Population
3,515
Median household income
$170,598
Typical home value
$636,200+4.2% in 12 months
Median rent
—gross, per month
Median age
48.6
Homeowners
95.5%of occupied homes
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Shaded: ZIP code 63341's area. Click anywhere on the map to see which ZIP code it's in.

ZIP codes within 10 milesWithin 25 miles

ZIP code 63341 details

CityDefiance
StateMissouri
CountySt. Charles County
Metro areaSt. Louis, MO-IL
Time zoneCentral Time (UTC−6), observes daylight saving time
TypeStandard (delivery area)
Land area38.8 sq mi, plus 1.1 sq mi of water
Population density91 people per sq mi
Bachelor's degree or higher54.1% of adults 25+
Average commute28.7 minutes
Center coordinates38.66063, -90.80679

ZIP codes near 63341

ZIP codeCityDistancePopulation
63365New Melle, MO4.9 mi51
63073Saint Albans, MO5.6 mi803
63332Augusta, MO6.4 mi1,651
63304Saint Charles, MO7.2 mi43,195
63368O Fallon, MO7.6 mi46,966
63367Lake Saint Louis, MO7.9 mi29,725
63005Chesterfield, MO8.5 mi19,779
63055Labadie, MO9.2 mi1,693

Population and median household income: ACS 2020–2024 5-year estimates. Typical home value: Zillow Home Value Index (September 2026) where available, otherwise the ACS median owner-reported value. "PO Box" marks ZIP codes with no delivery area of their own. Methodology

Buying a home in 63341?

A typical home in ZIP code 63341 is worth about $636,200 (Zillow Home Value Index). The median household here earns $170,598 a year. See what buying here would cost per month, with Missouri average taxes and insurance filled in.

Monthly payment for a $636,200 homeWhat can a $170,598 income afford?Rental property numbers

About ZIP code 63341

What city is ZIP code 63341?

ZIP code 63341 is in Defiance, MO, in St. Charles County.

What county is ZIP code 63341 in?

63341 is mainly in St. Charles County, Missouri.

What is the population of ZIP code 63341?

About 3,515 people live in ZIP code 63341, according to the American Community Survey 2020–2024 5-year estimates.

What time zone is ZIP code 63341 in?

63341 is in Central Time (UTC−6). It observes daylight saving time.