East Prairie, MO ZIP code
The ZIP code for East Prairie, Missouri is 63845. It is in Mississippi County.
- Population in these ZIPs
- 5,261
- Avg. median income
- $51,200population-weighted
- Typical home value
- $118,800population-weighted
- Metro area
- Sikeston, MO
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East Prairie, MO ZIP code list
| ZIP code | Population | Median income | Typical home value |
|---|---|---|---|
| 63845 | 5,261 | $51,207 | $118,800 |
Population and median household income: ACS 2020–2024 5-year estimates. Typical home value: Zillow Home Value Index (September 2026) where available, otherwise the ACS median owner-reported value. "PO Box" marks ZIP codes with no delivery area of their own. Methodology
Cities near East Prairie
Frequently asked questions
What is the ZIP code for East Prairie, MO?
The ZIP code for East Prairie, MO is 63845.
What county is East Prairie, Missouri in?
East Prairie ZIP codes are in Mississippi County.