Mississippi County, Missouri ZIP codes
6 ZIP codes are in Mississippi County, plus 1 that cross in from neighboring counties. It's part of the Sikeston, MO micro area.
- ZIP codes
- 6
- Population in these ZIPs
- 12,435
- Avg. median income
- $47,800population-weighted
- Cities & towns
- 6
Click anywhere on the map to see which ZIP code it's in.
ZIP codes in Mississippi County
| ZIP code | City | Population | Median income | Typical home value |
|---|---|---|---|---|
| 63820 | Anniston | 249 | — | — |
| 63823 | Bertrand | 1,434 | $62,656 | $123,800 |
| 63834 | Charleston | 5,169 | $41,348 | $99,900 |
| 63845 | East Prairie | 5,261 | $51,207 | $118,800 |
| 63881 PO Box | Wolf Island | — | — | — |
| 63882 | Wyatt | 322 | $30,227 | $57,100 |
ZIP codes partly in Mississippi County
These ZIP codes are mostly in a neighboring county but cover part of Mississippi County.
| ZIP code | City | County | Population | Median income | Typical home value |
|---|---|---|---|---|---|
| 63801 | Sikeston | Scott County | 22,027 | $62,698 | $161,200 |
Population and median household income: ACS 2020–2024 5-year estimates. Typical home value: Zillow Home Value Index (September 2026) where available, otherwise the ACS median owner-reported value. "PO Box" marks ZIP codes with no delivery area of their own. Methodology
Cities and towns in Mississippi County
Nearby counties
Frequently asked questions
How many ZIP codes are in Mississippi County, Missouri?
6 ZIP codes are mainly in Mississippi County, and 1 more ZIP codes from neighboring areas reach partly into it.
What cities are in Mississippi County?
ZIP codes in Mississippi County use the city names Anniston, Bertrand, Charleston, East Prairie, Wolf Island and Wyatt.
What metro area is Mississippi County in?
Mississippi County is part of the Sikeston, MO micropolitan statistical area.