ZIP code 49221: Adrian, MI
49221 is a ZIP code in Adrian, Michigan, mainly in Lenawee County, part of the Adrian, MI micro area. About 41,087 people live here.
- Population
- 41,087
- Median household income
- $65,977
- Typical home value
- $211,200+5.1% in 12 months
- Median rent
- $992gross, per month
- Median age
- 41.1
- Homeowners
- 71.1%of occupied homes
Shaded: ZIP code 49221's area. Click anywhere on the map to see which ZIP code it's in.
ZIP codes within 10 milesWithin 25 miles
ZIP code 49221 details
| City | Adrian |
|---|---|
| State | Michigan |
| County | Lenawee County |
| Metro area | Adrian, MI |
| Time zone | Eastern Time (UTC−5), observes daylight saving time |
| Type | Standard (delivery area) |
| Land area | 119.9 sq mi, plus 0.7 sq mi of water |
| Population density | 343 people per sq mi |
| Bachelor's degree or higher | 22.3% of adults 25+ |
| Average commute | 23.7 minutes |
| Center coordinates | 41.90235, -84.06470 |
Median rent in 49221 by bedrooms
| Size | Median gross rent |
|---|---|
| 1 bedroom | $850/mo |
| 2 bedrooms | $1,069/mo |
| 3 bedrooms | $1,176/mo |
| 4 bedrooms | $1,009/mo |
| 5+ bedrooms | $869/mo |
Gross rent includes utilities paid by the tenant. ACS 2020–2024; sizes with too few rentals to estimate are left out.
ZIP codes near 49221
| ZIP code | City | Distance | Population |
|---|---|---|---|
| 49268 | Palmyra, MI | 7.4 mi | 1,108 |
| 49235 | Clayton, MI | 7.5 mi | 2,115 |
| 49287 | Tipton, MI | 8.4 mi | 1,958 |
| 49279 | Sand Creek, MI | 8.7 mi | 965 |
| 49265 | Onsted, MI | 9.2 mi | 5,157 |
| 49289 | Weston, MI | 9.3 mi | 129 |
| 49286 | Tecumseh, MI | 10.1 mi | 14,128 |
| 49248 | Jasper, MI | 10.4 mi | 787 |
Population and median household income: ACS 2020–2024 5-year estimates. Typical home value: Zillow Home Value Index (September 2026) where available, otherwise the ACS median owner-reported value. "PO Box" marks ZIP codes with no delivery area of their own. Methodology
Buying a home in 49221?
A typical home in ZIP code 49221 is worth about $211,200 (Zillow Home Value Index). The median household here earns $65,977 a year. See what buying here would cost per month, with Michigan average taxes and insurance filled in.
Monthly payment for a $211,200 homeWhat can a $65,977 income afford?Rental property numbers
About ZIP code 49221
What city is ZIP code 49221?
ZIP code 49221 is in Adrian, MI, in Lenawee County.
What county is ZIP code 49221 in?
49221 is mainly in Lenawee County, Michigan.
What is the population of ZIP code 49221?
About 41,087 people live in ZIP code 49221, according to the American Community Survey 2020–2024 5-year estimates.
What time zone is ZIP code 49221 in?
49221 is in Eastern Time (UTC−5). It observes daylight saving time.