ZIP code 45681: South Salem, OH
45681 is a ZIP code in South Salem, Ohio, mainly in Ross County, part of the Chillicothe, OH micro area. About 1,451 people live here.
- Population
- 1,451
- Median household income
- $49,510
- Typical home value
- $189,400+4% in 12 months
- Median rent
- $693gross, per month
- Median age
- 50.9
- Homeowners
- 79.4%of occupied homes
Shaded: ZIP code 45681's area. Click anywhere on the map to see which ZIP code it's in.
ZIP codes within 10 milesWithin 25 miles
ZIP code 45681 details
| City | South Salem |
|---|---|
| State | Ohio |
| County | Ross County |
| Metro area | Chillicothe, OH |
| Time zone | Eastern Time (UTC−5), observes daylight saving time |
| Type | Standard (delivery area) |
| Land area | 36.2 sq mi, plus 0 sq mi of water |
| Population density | 40 people per sq mi |
| Bachelor's degree or higher | 10.6% of adults 25+ |
| Average commute | 31 minutes |
| Center coordinates | 39.29974, -83.25785 |
Median rent in 45681 by bedrooms
| Size | Median gross rent |
|---|---|
| 2 bedrooms | $693/mo |
| 3 bedrooms | $582/mo |
Gross rent includes utilities paid by the tenant. ACS 2020–2024; sizes with too few rentals to estimate are left out.
ZIP codes near 45681
| ZIP code | City | Distance | Population |
|---|---|---|---|
| 45617 | Bourneville, OH | 5.6 mi | 0 |
| 45612 | Bainbridge, OH | 6.5 mi | 4,933 |
| 45628 | Frankfort, OH | 7.1 mi | 5,999 |
| 45123 | Greenfield, OH | 7.8 mi | 8,740 |
| 45624 | Cynthiana, OH | 10.0 mi | 0 |
| 43115 | Clarksburg, OH | 13.9 mi | 1,796 |
| 45135 | Leesburg, OH | 15.6 mi | 5,291 |
| 45646 | Latham, OH | 15.9 mi | 129 |
Population and median household income: ACS 2020–2024 5-year estimates. Typical home value: Zillow Home Value Index (September 2026) where available, otherwise the ACS median owner-reported value. "PO Box" marks ZIP codes with no delivery area of their own. Methodology
Buying a home in 45681?
A typical home in ZIP code 45681 is worth about $189,400 (Zillow Home Value Index). The median household here earns $49,510 a year. See what buying here would cost per month, with Ohio average taxes and insurance filled in.
Monthly payment for a $189,400 homeWhat can a $49,510 income afford?Rental property numbers
About ZIP code 45681
What city is ZIP code 45681?
ZIP code 45681 is in South Salem, OH, in Ross County.
What county is ZIP code 45681 in?
45681 is mainly in Ross County, Ohio.
What is the population of ZIP code 45681?
About 1,451 people live in ZIP code 45681, according to the American Community Survey 2020–2024 5-year estimates.
What time zone is ZIP code 45681 in?
45681 is in Eastern Time (UTC−5). It observes daylight saving time.