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ZIP code 21758: Knoxville, MD

21758 is a ZIP code in Knoxville, Maryland, mainly in Frederick County, part of the Washington-Arlington-Alexandria, DC-VA-MD-WV metro area. About 4,409 people live here.

Population
4,409
Median household income
$111,528
Typical home value
$461,300+0.5% in 12 months
Median rent
$1,770gross, per month
Median age
39
Homeowners
84.4%of occupied homes
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Shaded: ZIP code 21758's area. Click anywhere on the map to see which ZIP code it's in.

ZIP codes within 10 milesWithin 25 miles

ZIP code 21758 details

CityKnoxville
StateMaryland
CountyFrederick County (also partly Washington County)
Metro areaWashington-Arlington-Alexandria, DC-VA-MD-WV
Time zoneEastern Time (UTC−5), observes daylight saving time
TypeStandard (delivery area)
Land area32 sq mi, plus 2.8 sq mi of water
Population density138 people per sq mi
Bachelor's degree or higher43.7% of adults 25+
Average commute36.1 minutes
Center coordinates39.35321, -77.65681

Median rent in 21758 by bedrooms

SizeMedian gross rent
2 bedrooms$1,856/mo
3 bedrooms$1,851/mo

Gross rent includes utilities paid by the tenant. ACS 2020–2024; sizes with too few rentals to estimate are left out.

ZIP codes near 21758

ZIP codeCityDistancePopulation
21715Brownsville, MD1.8 mi20
21716Brunswick, MD2.9 mi7,200
21718Burkittsville, MD3.2 mi134
21755Jefferson, MD4.8 mi5,909
21779Rohrersville, MD4.9 mi1,311
20180Lovettsville, VA5.9 mi7,531
25425Harpers Ferry, WV7.0 mi13,332
21756Keedysville, MD7.6 mi3,640

Population and median household income: ACS 2020–2024 5-year estimates. Typical home value: Zillow Home Value Index (September 2026) where available, otherwise the ACS median owner-reported value. "PO Box" marks ZIP codes with no delivery area of their own. Methodology

Buying a home in 21758?

A typical home in ZIP code 21758 is worth about $461,300 (Zillow Home Value Index). The median household here earns $111,528 a year. See what buying here would cost per month, with Maryland average taxes and insurance filled in.

Monthly payment for a $461,300 homeWhat can a $111,528 income afford?Rental property numbers

About ZIP code 21758

What city is ZIP code 21758?

ZIP code 21758 is in Knoxville, MD, in Frederick County.

What county is ZIP code 21758 in?

21758 is mainly in Frederick County, Maryland, and partly in Washington County.

What is the population of ZIP code 21758?

About 4,409 people live in ZIP code 21758, according to the American Community Survey 2020–2024 5-year estimates.

What time zone is ZIP code 21758 in?

21758 is in Eastern Time (UTC−5). It observes daylight saving time.