Santee, SC ZIP code
The ZIP code for Santee, South Carolina is 29142. It is in Orangeburg County.
- Population in these ZIPs
- 4,744
- Avg. median income
- $54,000population-weighted
- Typical home value
- $245,100population-weighted
- Metro area
- Orangeburg, SC
Loading map…
Click anywhere on the map to see which ZIP code it's in.
Santee, SC ZIP code list
| ZIP code | Population | Median income | Typical home value |
|---|---|---|---|
| 29142 | 4,744 | $54,028 | $245,100 |
Population and median household income: ACS 2020–2024 5-year estimates. Typical home value: Zillow Home Value Index (September 2026) where available, otherwise the ACS median owner-reported value. "PO Box" marks ZIP codes with no delivery area of their own. Methodology
Cities near Santee
- Vance 5 mi
- Elloree 6 mi
- Bowman 10 mi
- Cameron 11 mi
- Holly Hill 11 mi
- Summerton 12 mi
- Eutawville 14 mi
- Harleyville 15 mi
- Pinewood 16 mi
- Rowesville 18 mi
- Orangeburg 19 mi
- Reevesville 21 mi
Frequently asked questions
What is the ZIP code for Santee, SC?
The ZIP code for Santee, SC is 29142.
What county is Santee, South Carolina in?
Santee ZIP codes are in Orangeburg County.